Эбрасодебарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2572467-73-1

immunoglobulin G4-lambda2, anti-[Homo sapiens TMEM219 (transmembrane protein 219, insulin-like growth factor-binding protein 3 receptor, IGFBP-3R) extracellular domain], Homo sapiens monoclonal antibody;
H-gamma4 heavy chain Homo sapiens (1-444) [VH (Homo sapiens IGHV1-18*01 (99.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v3 CH2 E1.2 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307), L1.2>E (233) (229-338), CH3 (339-443), CHS K2>del (444)) (119-444)], (132-213')-disulfide with L-lambda2 light chain Homo sapiens (1'-214') [V-LAMBDA (Homo sapiens IGLV3-1*01 (90.1%) -IGLJ2*01 (100%), CDR-IMGT [6.3.11] (26'-31'.49'-51'.88'-98')) (1'-108') -Homo sapiens IGLC2*01 (100%) (109'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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