Эфдамрофусп альфа

Rec. INN (наименование, зарегистрированное ВОЗ)

2375661-82-6

human vascular endothelial growth factor receptor 1 (VEGFR-1) immunoglobulin-like domain 2 containing fragment (104-204, 1-101 in the current sequence), fused via human vascular endothelial growth factor receptor 2 (VEGFR-2) immunoglobulin-like domain 3 containing fragment (206-308, 102-204 in the current sequence) to human immunoglobulin G1 Fc fragment (205-431), fused via peptidyl linker ⁴³²GGGGGG⁴³⁷ to human complement receptor type 1 (CR1) fragment (1-192, 438-629 in the current sequence) variant (N²⁹>K⁴⁶⁶, S³⁷>Y⁴⁷⁴, G⁷⁹>D⁵¹⁶, D¹⁰⁹>N⁵⁴⁶), dimer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa;
VEGFR1/VEGFR2 fragments-IgG1 Fc-CR1 fusion protein: human vascular endothelial growth factor receptor 1 (VEGFR1) (104-204)- peptide (containing the Ig-like C2-type domain 2) (1-101) / human vascular endothelial growth factor receptor 2 (VEGFR2) (206-308)- peptide (containing the Ig-like C2-type domain 3) (102-204) / human immunoglobulin G1 heavy chain constant region C-terminal 227-peptide fragment (IgG1 Fc) (205-431) [Homo sapiens IGHG1*01; hinge: 205- 214; CH2: 215-324; CH3: 325-429; CHS: 430-431] / G⁶ peptide linker (432-437) / human complement receptor type 1 (CR1) [N²⁹>K⁴⁶⁶, S³⁷>Y⁴⁷⁴, G⁷⁹>D⁵¹⁶, D¹⁰⁹>N⁵⁴⁶] (1-192)-peptide (438-629) fusion protein, dimer (210-210':213-213')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

C₆₂₄₀H₉₇₀₈N₁₇₀₀O₁₈₇₄S₅₈

Поделиться этой страницей