Эфлимруфусп альфа

Rec. INN (наименование, зарегистрированное ВОЗ)

2363779-14-8

human vascular endothelial growth factor receptor 1 (VEGFR-1) immunoglobulin-like domain 2 containing fragment (132-232, 1-101 in the current sequence), fused via human vascular endothelial growth factor receptor 2 (VEGFR-2) immunoglobulin-like domain 3 containing fragment (227-327, 102-202 in the current sequence) to human fibroblast growth factor receptor 1 (FGFR-1) immunoglobulin-like domains 2 and 3 containing fragment (150-361, 203-414 in the current sequence), fused to human immunoglobulin G1 Fc fragment (415-641), dimer, glycosylated, produced in Chinese hamster ovary (CHO) cells;
vascular endothelial growth factor receptor 1 (Homo sapiens VEGFR-1) (132-232)-peptide (1-101), containing the immunoglobulin-like domain 2, fused with vascular endothelial growth factor receptor 2 (Homo sapiens VEGFR-2) (227-327)-peptide (102-202), containing the immunoglobulin-like domain 3, with fibroblast growth factor receptor 1 (Homo sapiens FGFR-1) (150-361)-peptide (203­414), containing the immunoglobulin-like domains 2 and 3 (211-299 and 308-410), and with a C-terminal Homo sapiens immunoglobulin G1 227-peptide Fc fragment (415­641), [Homo sapiens IGHG1*01; hinge 415-424; CH2: 425­534; CH3: 535-639; CHS: 640-641]; dimer (420-420':423- 423')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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