Эфсубаглутид альфа

Prop. INN (наименование, предложенное ВОЗ)

2803875-75-2

glucagon-like peptide-1-immunoglobulin G2 fusion protein; {[2-glycine,16-L-glutamic acid,30-glycine][human glucagon-like peptide 1-(7-37)-peptide] {(8-A>G,22-G>E,36-R>G)-GLP-1(7-37)} (1-31)}- [SSGAPPPSGGGGS linker (32-44)]-[human immunoglobulin G2 Fc fragment (h-CH2-CH3-CHS domains [Homo sapiens IGHG2*01 (hinge C⁴⁸>S (45-56), CH2 A¹⁵⁵>S, P¹⁵⁶>S (57-165),CH3 (166-270), CHS K²⁷²>del (271))] (45-271)] fusion protein, dimer (49-49':52-52':55-55':86-146:86'- 146':192-250:192'-250')-heptakisdisulfide, produced in Chinese hamster ovary cells (CHO), glycoform alfa

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