Эфзимфотаза альфа

Rec. INN (наименование, зарегистрированное ВОЗ)

2746354-58-3

human alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP, TNS-ALP, EC:3.1.3.1) soluble fragment (1-491), variant (E¹⁰⁸>M, N²¹³>Q, N²⁸⁶>Q) fused to a human immunoglobulin G4 heavy chain constant region fragment (492-714) [Homo sapiens IGHG4*01; hinge: 492-498 (ERKCC 491-492del, P492V, P493E, S496P (matches IGHG2*02)); CH2: 499-607 (E501P, F502V, L503A, G503-504del (matches IGHG2*02)); CH3: 608-712; CHS: 713-714], fused to a deca-aspartate peptide (⁷¹⁵DDDDDDDDDD⁷²⁴), disulfide bridged dimer, produced in Chinese hamster ovary (CHO) cells, cell line K1SV, glycoform alfa

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