Эглатопрутуг
EglatoprutugМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2518200-21-8
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens KIT (KIT proto-oncogene receptor tyrosine kinase, c-kit, SCFR, CD117)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV1-46*01 (87.8%) -(IGHD) -IGHJ6*01 (90.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS K2>del (446)) (118-446)], (220-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA (Homo sapiens IGKV2-28*01 (80.0%) -IGKJ4*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (226-226'': 229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1 lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV1-46*01 (87.8%) -(IGHD) -IGHJ6*01 (90.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS K2>del (446)) (118-446)], (220-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA (Homo sapiens IGKV2-28*01 (80.0%) -IGKJ4*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (226-226'': 229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1 lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Структура
Иностранные названия
- Eglatoprutugum (латинское)
- Eglatoprutug (английское)
- Eglatoprutug (немецкое)
- Églatoprutug (французское)
- Eglatoprutug (испанское)
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