Эмактузумаб

USP (Фармакопея США)

DB14905

1448221-67-7

immunoglobulin G1-kappa, anti-[Homo sapiens CSF1R (colony stimulating factor 1 receptor, CSF-1R, CSF-1-R, macrophage colony-stimulating factor 1 receptor, c-fms, FMS, CD115)], humanized monoclonal antibody;
gamma1 heavy chain (1-446) [humanized VH (Homo sapiens IGHV1-18*01 (92.90%) -(IGHD)-IGHJ6*01) [8.7.10] (1-116) -Homo sapiens IGHG1*01 (CH1 (117- 214), hinge (215-229), CH2 (230-339), CH3 (340-444), CHS (445-446)) (117-446)], (219-213')-disulfide with kappa light chain (1’-213’) [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (86.30%) -IGKJ2*01) [6.3.8] (1'-106') -Homo sapiens IGKC*01 (107'-213')]; dimer (225-225":228-228")- bisdisulfide

C₆₃₉₈H₉₉₀₈N₁₇₀₄O₂₀₂₀S₄₄

144430,19 г/моль

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