Этесевимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15897

2423948-94-9

immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-66*01 (96.9%) -(IGHD) - IGHJ4*01 (100%)) CDR-IMGT [8.7.13] (26-33.51-57.96-108) (1-119) -Homo sapiens IGHG1*03 G1m3, nG1m1, G1v14 A1.3, A1.2 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237), (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-216')-disulfide with kappa light chain Homo sapiens (1’-216’) [V-KAPPA (Homo sapiens IGKV1-39*01 (97.9%) -IGKJ2*01 (100%)) CDR-IMGT [6.3.11] (27-32.50-52.89-99) (1'-109') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (155), V101 (193) (110'-216')]; dimer (228-228":231-231")-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line derived from CHO-K1SV, lacking the Glutamine Synthetase (GS) gene, glycoform alfa

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