Элегробарт

Prop. INN (наименование, предложенное ВОЗ)

2832924-76-0

immunoglobulin G1-kappa, anti-[Homo sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], monoclonal antibody;
H-gamma1 heavy chain (1-453) [VH Musmus/Homsap (Mus musculus IGHV1-69-5*01 (92.9%) -(IGHD) -IGHJ1*01 (93.8%) A120>Q (116)/Homo sapiens IGHV1-46*01 (77.6%) C104>F (96) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (221) (125-222), hinge 1-15 (223-237), CH2 M15.1>Y (259), S16>T (261), T18>E (263) (238-347), CH3 D12 (363), L14 (365) (348-452), CHS K2>del (453)) (125-453)], (227-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-117*01 (93.0%) -IGKJ1*02 (100%)/Homo sapiens IGKV2-30*02 (81.0%) -IGKJ4*01 (90.9%) V124>L (109'), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (233-233'':236-236'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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