Элритерцепт

Rec. INN (наименование, зарегистрированное ВОЗ)

2727114-26-1

human activin receptor type 2-A (activin receptor type IIA, ACTR-IIA) extracellular domain (ECD) fragment (1-109) engineered variant (F¹⁵>Y, ²¹KD²²>LE, P³¹>R, Y³³>E, D³⁵>E, R⁴⁰>L, F⁴³>Y, K⁴⁷>R, Q⁵⁸>K, I⁶⁵>F, ⁷⁶KKDS⁷⁹>TEEN, E⁸¹>Q) fused via the peptide linker ¹¹⁰GGG¹¹² to a human immunoglobulin G1 heavy chain fragment C-terminal Fc fragment (113-338), [Homo sapiens IGHG1*01; hinge: 113-122 (EPKSC 112- 113del); CH2: 123-232; CH3: 233-337; CHS: 338-338 (K339del)]; disulfide bridged dimer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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