Элтивутабарт

Prop. INN (наименование, предложенное ВОЗ)

2935496-38-9

immunoglobulin G4-kappa, anti-[Homo sapiens ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1, CD39)], Homo sapiens monoclonal antibody;
H-gamma4 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-46*02 (94.9%) -(IGHD) -IGHJ5*02 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (96.7%) -IGKJ4*01 (91.7%), CDR-IMGT [7.3.8] (27'-33'.51'-53'.90'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44 lacking the enzyme dihydrofolate reductase (DHFR), glycoform alfa

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