Элтрекибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2484883-56-7

immunoglobulin G4-kappa, anti-[Homo sapiens CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7 and CXCL8 (C-X-C chemokines with the Glu-Leu-Arg (ELR) motif)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-46*01 (86.7%) -(IGHD) -IGHJ4*01 (92.3%), CDR-IMGT [8.8.19] (26-33.51-58.97-115)) (1-126) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (127-224), hinge 1-12 S10>P (234) (225-236), CH2 L92 (315) (237-346), CH3 (347-451), CHS K2>del (452)) (127-452)], (140-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (85.3%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-derived cell line transfected with the glutamine synthetase (GS) gene, glycoform alfa

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