Эмпасипрубарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2579031-19-7

immunoglobulin G1-kappa, anti-[Homo sapiens C2 (complement 2)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-447) [VH humanized (Homo sapiens IGHV1-8*01 (82.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1, G1v14 CH2 A1.3, A1.2, G1v46 CH3 K113, F114 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 L1.3>A (235), L1.2>A (236) (232-341), CH3 D12 (357), L14 (359), H113>K (434), N114>F (435) (342-446), CHS K2>del (447)) (119-447)], (221-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA (Homo sapiens IGKV4-1*01 (74.3%) -IGKJ2*01 (100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (157), V101 (195) (112'-218')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

Поделиться этой страницей