Энаватузумаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

1062149-33-0

immunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF12A (tumor necrosis factor receptor superfamily member 12A, fibroblast growth factor (FGF)-inducible 14 kDa protein, Fn14, TNF-like weak inducer of apoptosis (Tweak) receptor, Tweak receptor, TweakR, CD266], humanized monoclonal antibody;
gamma1 heavy chain (1-449) [humanized VH (Homo sapiens IGHV3-7*01 (86.70%) -(IGHD)-IGHJ6*01 T123>L (114)) [8.10.10] (1-119) -Homo sapiens IGHG1*01 CH3 D12>E (358), L14>M (360) (120-449)], (222-218')-disulfide with kappa light chain (1'-218') [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (84.80%) - IGKJ4*01) [10.3.9] (1'-111') -Homo sapiens IGKC*01 (112'-218')]; (228-228":231-231")-bisdisulfide dimer

C₆₄₉₄H₁₀₀₀₄N₁₇₂₀O₂₀₃₈S₄₈

143104,43 г/моль

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