Эноблитузумаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15017

1353485-38-7

immunoglobulin G1-kappa, anti-[Homo sapiens CD276 (B7H3, B7-H3, B7RP-2)], humanized monoclonal antibody;
gamma1 heavy chain (1-452) [humanized VH (Homo sapiens IGHV3-48*02 (91.80%) -(IGHD) -IGHJ6*01) [8.8.15] (1-122) -Homo sapiens IGHG1*03 (CH1 (123- 220), hinge (221-235), CH2 L1.2>V (240), F7>L (248), R83>P (297), Y85.2>L (305) (236-345), CH3 P83>L (401) (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1D-13*01 (85.10%) -IGKJ2*01) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 (108'-214')]; dimer (231-231":234-234")-bisdisulfide

C₆₄₇₄H₉₉₉₀N₁₇₂₆O₂₀₃₀S₄₂

145829,71 г/моль

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