Энузовимаб
EnuzovimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2531098-91-4
Химическое название
immunoglobulin G4-kappa, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-53*01 (95.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.12] (26-33.51-57.96-107)) (1-118)-Homo sapiens IGHG4*01, G4v5 h P10, G4v21 CH2 Y15.1, T16, E18 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 M15.1>Y (250), S16>T(252), T18>E (254) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (98.9%) -IGKJ2*01 (100%), CDR- IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-53*01 (95.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.7.12] (26-33.51-57.96-107)) (1-118)-Homo sapiens IGHG4*01, G4v5 h P10, G4v21 CH2 Y15.1, T16, E18 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 M15.1>Y (250), S16>T(252), T18>E (254) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (98.9%) -IGKJ2*01 (100%), CDR- IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Enuzovimabum (латинское)
- Enuzovimab (английское)
- Enuzovimab (немецкое)
- Énuzovimab (французское)
- Enuzovimab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Энузовимаб: