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Rec. INN (наименование, зарегистрированное ВОЗ)

2410976-61-1

immunoglobulin G2-kappa, anti-[Homo sapiens INSR (insulin receptor)], Homo sapiens monoclonal antibody, allosteric;
gamma2 heavy chain Homo sapiens (1-444) [VH (Homo sapiens IGHV3-30*01 (98.0%) -(IGHD) -IGHJ6*01 (93.8%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG2*02 (100%), G2m23 CH2 M45.1 (CH1 (119-216), hinge 1-12 (217-228), CH2 M45.1 (279) (229-337), CH3 (338-442), CHS (443-444)) (119-444)], (132-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2-30*01 (93.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01, Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (220-220'':221-221'':224-224'':227-227'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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