Этедесиран

Etedesiran

МНН

Prop. INN Mod. (наименование, предложенное ВОЗ, модифицированное наименование)

Химическое название

all-P-ambo-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-deoxy-2'-fluoro-P- thiouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')- 2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O- methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O- methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O- methylguanylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyl-P- thioguanylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridine duplex with all-P-ambo-(3RS)-1-({cis- or trans-4-[(6-{[2'-O-methyl-P-thioadenylyl-(5'→3')-2'-O-methyl-P-thioadenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O- methylcytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O- methylguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')- 2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyl-P-thiocytidylyl-(5'→3')-2'-O-methyl-P-thiocytidylyl-(5'→3')-2'-O-methyl-5'-cytidylyl]oxy}hexyl)carbamoyl]cyclohexyl}methyl)-2,5- dioxopyrrolidin-3-yl

Химическая формула

-C430H557F7N148O269P39S8

Структура

Структура Этедесиран

Иностранные названия

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