Этигилимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2044984-83-8

immunoglobulin G1-kappa, anti-[Homo sapiens TIGIT (T-cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], humanized monoclonal antibody;
gamma1 heavy chain (1-448) [Homo sapiens VH (IGHV4-59*01 (88.8%) -(IGHD)- IGHJ4*01 (92.9%)) [8.7.12] (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (215) (119-216), hinge (217-231), CH2 (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with kappa light chain (1’-214’) [Homo sapiens V-KAPPA (IGKV1-33*01 (85.3%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*05, Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (227-227":230-230")-bisdisulfide

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