Этокимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2022981-44-6

immunoglobulin G1-kappa, anti-[Homo sapiens IL33 (interleukin 33, interleukin-1 family member 11, IL1F11, nuclear factor for high endothelial venules, NF-HEV)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-46*01 (87.8%) -(IGHD) -IGHJ1*01 (100%)) [8.8.15] (1-122) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (219) (123-220), hinge (221-235), CH2 D12 (361), L14 (363) (236-345), CH3 (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-9*01 (85.3%) -IGKJ2*02 (90.9%)) [6.3.9] (1'-107') - Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (231-231":234-234")-bisdisulfide

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