Эвунзекибарт
EvunzekibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2639688-77-8
Химическое название
immunoglobulin G4-kappa, anti-[TNFRSF9 (tumor necrosis factor receptor (TNFR) superfamily member 9, 4-1BB, CD137)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-23*03 (88.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-39*01 (94.6%) -IGKJ2*02 (100%), CDR-IMGT [6.3.10] (27-32.50-52.89-98)) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-23*03 (88.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-39*01 (94.6%) -IGKJ2*02 (100%), CDR-IMGT [6.3.10] (27-32.50-52.89-98)) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa
Структура
Иностранные названия
- Evunzekibartum (латинское)
- Evunzekibart (английское)
- Evunzekibart (немецкое)
- Évunzékibart (французское)
- Evunzekibart (испанское)
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