Фалбикитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2740565-02-8

immunoglobulin G1-kappa, anti-[Homo sapiens LIF (LIF interleukin 6 family cytokine, leukemia inhibitory factor)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-15*07 (86.9%) -(IGHD) -IGHJ1*01 (90.9%), CDR-IMGT [8.10.9] (26-33.51-60.99-107)) (1-118) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV2-24*01 (90.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.10] (27-37.55-57.94-103)) (1'-113') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (159), V101 (197) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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