Фепикснебарт

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2489584-93-0

immunoglobulin G4-kappa, anti-[Homo sapiens TGFA (transforming growth factor alpha) and anti-EREG (epiregulin)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-444) [VH humanized (Homo sapiens IGHV1-69*02 (83,7%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, IGHG4v5 h P10, G4v4 CH2 A1.3, A1.2, nG4m(a) CH2 L92 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307), F1.3>A (232), L1.2>A (233) (229-338), CH3 (339-443), CHS K2>del (444)) (119-444)], (132-219')-disulfide with kappa light chain Homo sapiens (1'-219') [V-KAPPA Homo sapiens IGKV4-1*01 (81.2%) -IGKJ4*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-derived cell line transfected with the glutamine synthetase (GS) gene, glycoform alfa

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