Финотонлимаб
FinotonlimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2350298-85-8
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD-1, PD1, CD279)], monoclonal antibody;
gamma4 heavy chain (1-445) [VH (Mus musculus IGHV5-9-2*01 (88.8%) -(IGHD) -IGHJ4*01 (90.9%)/Homo sapiens IGHV3-23*04 (86.7%) -(IGHD) -IGHJ3*01 (90.9%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-218')-disulfide with kappa light chain (1'-218') [V-KAPPA (Homo sapiens IGKV3D-11*02 (81.9%) -IGKJ1*01 (100%)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112’-218’)]; dimer (224-224":227-227")-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma4 heavy chain (1-445) [VH (Mus musculus IGHV5-9-2*01 (88.8%) -(IGHD) -IGHJ4*01 (90.9%)/Homo sapiens IGHV3-23*04 (86.7%) -(IGHD) -IGHJ3*01 (90.9%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1-118) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-218')-disulfide with kappa light chain (1'-218') [V-KAPPA (Homo sapiens IGKV3D-11*02 (81.9%) -IGKJ1*01 (100%)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112’-218’)]; dimer (224-224":227-227")-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Finotonlimabum (латинское)
- Finotonlimab (английское)
- Finotonlimab (немецкое)
- Finotonlimab (французское)
- Finotonlimab (испанское)
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