Физтасовимаб
FiztasovimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2467411-25-0
Химическое название
immunoglobulin G1-lambda2, anti-[human betaherpesvirus 5 (HHV-5, human cytomegalovirus, HCMV) envelope glycoprotein B (gB) domain 1 (AD-1)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV4-34*01 (93.8%) -(IGHD) -IGHJ6*04 (93.8%), CDR-IMGT [8.7.18] (26-33.51-57.96-113)) (1-124) -Homo sapiens IGHG1*07p (100%), G1m17,1,2 (CH1 K120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 D12 (363), L14 (365), G110 (438) (348-452), CHS (453-454)) (125-454)], (227-215')-disulfide with lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV1-47*01 (93.9%) -IGLJ1*01 (100%), CDR-IMGT [8.3.11] (26-33.51-53.90-100)) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV4-34*01 (93.8%) -(IGHD) -IGHJ6*04 (93.8%), CDR-IMGT [8.7.18] (26-33.51-57.96-113)) (1-124) -Homo sapiens IGHG1*07p (100%), G1m17,1,2 (CH1 K120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 D12 (363), L14 (365), G110 (438) (348-452), CHS (453-454)) (125-454)], (227-215')-disulfide with lambda2 light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV1-47*01 (93.9%) -IGLJ1*01 (100%), CDR-IMGT [8.3.11] (26-33.51-53.90-100)) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, glycoform alfa
Структура
Иностранные названия
- Fiztasovimabum (латинское)
- Fiztasovimab (английское)
- Fiztasovimab (немецкое)
- Fiztasovimab (французское)
- Fiztasovimab (испанское)
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