Галегенимаб
GalegenimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2403683-24-7
Химическое название
immunoglobulin Fab G1-kappa, anti-[Homo sapiens HTRA1 (HtrA serine peptidase 1, protease serine 11 (IGF binding), PRSS11, IGFBP5-protease, ARMD7)], humanized monoclonal antibody;
VH-(CH1-hinge) gamma1 heavy chain humanized (1-223) [VH (Homo sapiens IGHV1-46*01 (77.6%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -CH1-hinge (Homo sapiens IGHG1*01 (100%), G1m17 (CH1 K120 (216) (120-217), hinge 1-7 (218-223)) (120-223)], (222-213')-disulfide with kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV1-39*01 (84.2%) -IGKJ1*01 (100%), CDR-IMGT [5.3.9] (27-31.49-51.88-96)) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')], produced in the bacteria Escherichia coli (E. coli), non-glycosylated
VH-(CH1-hinge) gamma1 heavy chain humanized (1-223) [VH (Homo sapiens IGHV1-46*01 (77.6%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -CH1-hinge (Homo sapiens IGHG1*01 (100%), G1m17 (CH1 K120 (216) (120-217), hinge 1-7 (218-223)) (120-223)], (222-213')-disulfide with kappa light chain humanized (1'-213') [V-KAPPA (Homo sapiens IGKV1-39*01 (84.2%) -IGKJ1*01 (100%), CDR-IMGT [5.3.9] (27-31.49-51.88-96)) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')], produced in the bacteria Escherichia coli (E. coli), non-glycosylated
Структура
Иностранные названия
- Galegenimabum (латинское)
- Galegenimab (английское)
- Galegenimab (немецкое)
- Galégénimab (французское)
- Galegenimab (испанское)
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