Гинисортамаб
GinisortamabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2390147-17-6
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens GREM1 (gremlin 1 DAN family BMP antagonist, cystine knot protein superfamily 1 BMP antagonist 1, CKTSF1B1, hereditary mixed polyposis syndrome, HMPS)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV1-69-2*01 (98.0%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-219')-disulfide with kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV4-1*01 (97.0%) -IGKJ5*01 (100%), CDR-IMGT [12.3.8] (27-38.56-58.95-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma4 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV1-69-2*01 (98.0%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG4*01, G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-219')-disulfide with kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV4-1*01 (97.0%) -IGKJ5*01 (100%), CDR-IMGT [12.3.8] (27-38.56-58.95-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Ginisortamabum (латинское)
- Ginisortamab (английское)
- Ginisortamab (немецкое)
- Ginisortamab (французское)
- Ginisortamab (испанское)
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