Грезирубарт
GreziprubartМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
2894136-80-0
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens C5 (complement 5) anaphylatoxin (C5a, C5 Pr678-751)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-72*01 (88.8%) -(IGHD) -IGHJ5*01 (91.7%) T122>V (113), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
H-gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-72*01 (88.8%) -(IGHD) -IGHJ5*01 (91.7%) T122>V (113), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120>K (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Greziprubartum (латинское)
- Greziprubart (английское)
- Greziprubart (немецкое)
- Gréziprubart (французское)
- Greziprubart (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Грезирубарт: