Идактамаб
IdactamabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2245205-37-0
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens SLC1A5 (solute carrier family 1 member 5, neutral amino acid transporter, RDRC, M7V1, AAAT, ASCT2)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV4-34*01 (96.9%) -(IGHD) -IGHJ4*01 (100%)) [8.7.15] (1-121) -Homo sapiens IGHG1*03 G1m3, nG1m1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 3^4>ins^cysteinyl (244) (235-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (122-452)], (224-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*03 (94.7%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)];
dimer (230-230'':233-233'')-bisdisulfide, glycoform alfa, produced in a Chinese Hamster Ovary (CHO) cell line derived from CHO-K1
gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV4-34*01 (96.9%) -(IGHD) -IGHJ4*01 (100%)) [8.7.15] (1-121) -Homo sapiens IGHG1*03 G1m3, nG1m1 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 3^4>ins^cysteinyl (244) (235-345), CH3 E12 (361), M14 (363) (346-450), CHS (451-452)) (122-452)], (224-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*03 (94.7%) -IGKJ1*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)];
dimer (230-230'':233-233'')-bisdisulfide, glycoform alfa, produced in a Chinese Hamster Ovary (CHO) cell line derived from CHO-K1
Структура
Иностранные названия
- Idactamabum (латинское)
- Idactamab (английское)
- Idactamab (немецкое)
- Idactamab (французское)
- Idactamab (испанское)
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