Илтамиоцел

Rec. INN (наименование, зарегистрированное ВОЗ)

Autologous human skeletal muscle progenitor cells derived from muscle biopsy (vastus lateralis). The progenitor cells are isolated by enzymatic digestion and expanded in culture in growth media containing human recombinant basic fibroblast growth factor (rbFGF), human recombinant endothelial growth factor (rEGF) and fetal bovine serum (FBS). Cell function and phenotype are maintained through control of culture confluence. The cells are positive for the myogenic cell marker desmin (on average 89%), and other muscle specific genes. The final substance contains also non-myogenic cell populations, such as fibroblasts. The cells have been demonstrated to have myogenic cell differentiation capacity.

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