Имапрелимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

2014343-04-3

immunoglobulin G1-kappa, anti-[Homo sapiens MCAM (melanoma cell adhesion molecule, gicerin, MUC18, CD146)], humanized monoclonal antibody;
gamma1 heavy chain (1-448) [humanized VH (Homo sapiens IGHV2-26*01 (82.0%) -(IGHD)-IGHJ4*01 (93.3%)) [8.7.12] (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1 (CH1 R120 (215) (119-216), hinge (217-231), CH2 L1.3>A (235), L1.2>A (236) (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-213')-disulfide with kappa light chain (1’-213’) [humanized V-KAPPA (Homo sapiens IGKV1-12*01 (85.6%) -IGKJ2*01 (100%)) [6.3.8] (1'-106') -Homo sapiens IGKC*01, Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (227-227":230-230")-bisdisulfide

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