Имдевимаб
ImdevimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB15940
CAS
2415933-40-1
Химическое название
immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-30*01 (96.9%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.13] (26-33.51-58.97-109) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (217) (121- 218),hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-215')-disulfide with lambda light chain Homo sapiens (1'-216') [V- LAMBDA (Homo sapiens IGLV2-14*01 (93.9%) - IGLJ3*02 (100%)) CDR-IMGT [9.3.10] (26-34.52-54.91-100) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (229-229":232-232")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-30*01 (96.9%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.13] (26-33.51-58.97-109) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 (CH1 K120 (217) (121- 218),hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-215')-disulfide with lambda light chain Homo sapiens (1'-216') [V- LAMBDA (Homo sapiens IGLV2-14*01 (93.9%) - IGLJ3*02 (100%)) CDR-IMGT [9.3.10] (26-34.52-54.91-100) (1'-110') -Homo sapiens IGLC2*01 (100%) (111'-216')]; dimer (229-229":232-232")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Imdevimabum (латинское)
- Imdevimab (английское)
- Imdévimab (немецкое)
- Imdevimab (французское)
- Imdevimab (испанское)
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