Имдусиран

Imdusiran

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

CAS

2839476-19-4

Химическое название

all-P-ambo-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-3'-O-[{[(3RS,4SR)-1-(10-{[(2S)-1,5-bis{[2-(3,5-bis{[2-(2-{2-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]ethoxy}ethoxy)ethyl]carbamoyl}anilino)-2-oxoethyl]amino}-1,5-dioxopentan-2-yl]amino}-10-oxodecanoyl)-4-(hydroxymethyl)-3,4-dimethylpyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]-2'-O-methyladenosineduplex with all-P-ambo-uridylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-(5'→3')-2'-O-methyladenylyl-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioguanylyl-(5'→3')-2'-O-methyluridine

Химическая формула

C502H678F6N162O303P38S6

Структура

Структура Имдусиран

Иностранные названия

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