Имнескибарт

Prop. INN (наименование, предложенное ВОЗ)

2919583-43-8

immunoglobulin G1-kappa, anti-[Homo sapiens IL2RA (interleukin 2 receptor subunit alpha; IL-2RA, TAC, p55, CD25)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-24*01 (84.5%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.14] (26-35.51-58.97-110)) (1-121) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v14 CH2 A1.3, A1.2 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>A (239) (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (88.1%) -IGKJ4*01 (90.9%) G120>A (106'), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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