Индемакитуг
IndemakitugМНН
Prop. INN (наименование, предложенное ВОЗ)
CAS
2856372-57-9
Химическое название
immunoglobulin G1-lambda1, anti-[Homo sapiens IFNG (interferon gamma, IFN gamma)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV3-21*01 (72.4%) -(IGHD) -IGHJ2*01 (100%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365) (348-452), CHS K2>del (453)) (125-453)], (227-216')-disulfide with L-lambda1 light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV6-57*03 (79.6%) -IGLJ2*01 (91.7%), CDR-IMGT [8.3.10] (26'-33'.51'-53'.92'-101')) (1'-111') -Homo sapiens IGLC1*02 (100%) (C-LAMBDA1) (112'-217')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1 lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
H-gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV3-21*01 (72.4%) -(IGHD) -IGHJ2*01 (100%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365) (348-452), CHS K2>del (453)) (125-453)], (227-216')-disulfide with L-lambda1 light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV6-57*03 (79.6%) -IGLJ2*01 (91.7%), CDR-IMGT [8.3.10] (26'-33'.51'-53'.92'-101')) (1'-111') -Homo sapiens IGLC1*02 (100%) (C-LAMBDA1) (112'-217')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1 lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Структура
Иностранные названия
- Indemakitugum (латинское)
- Indemakitug (английское)
- Indemakitug (немецкое)
- Indémakitug (французское)
- Indemakitug (испанское)
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