Инетагуген геперпавек
Inetagugene geperpavecМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
A replication-defective Herpes simplex virus encoding human transglutaminase 1 (TGM1).
A recombinant replication-deficient, non-integrating Herpes simplex virus type 1 (HSV-1) (strain KOS) vector encoding two copies of codon-optimised human transglutaminase 1 [TGM1, (EC:2.3.2.13)], also known as protein-glutamine gammaglutamyltransferase K (TGK) with both copies being expressed under the control of a human cytomegalovirus (hCMV) immediate early promoter and bovine growth hormone polyadenylation signal (bGH polyA). The vector was generated by deleting both copies of the viral immediate early (IE) gene ICP4 and inserting a copy of the TGM1 gene into each ICP4 locus. The vector is also deleted for the IE gene ICP22.
A recombinant replication-deficient, non-integrating Herpes simplex virus type 1 (HSV-1) (strain KOS) vector encoding two copies of codon-optimised human transglutaminase 1 [TGM1, (EC:2.3.2.13)], also known as protein-glutamine gammaglutamyltransferase K (TGK) with both copies being expressed under the control of a human cytomegalovirus (hCMV) immediate early promoter and bovine growth hormone polyadenylation signal (bGH polyA). The vector was generated by deleting both copies of the viral immediate early (IE) gene ICP4 and inserting a copy of the TGM1 gene into each ICP4 locus. The vector is also deleted for the IE gene ICP22.
Иностранные названия
- Inetagugenum geperpavecum (латинское)
- Inetagugene geperpavec (английское)
- Inetagugen geperpavec (немецкое)
- Inétagugène géperpavec (французское)
- Inetagugén geperpavec (испанское)
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