Изаралгаген цивапарвовек
Isaralgagene civaparvovecМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2378601-29-5
Химическое название
A non-replicating adeno-associated viral vector encoding codon-optimised human alpha-galactosidase A (GLA).
A recombinant, non-replicating adeno-associated viral vector serotype 6 (AAV6) encoding codon-optimised human alphagalactosidase A (GLA) under control of liver-specific regulatory elements [comprising enhancer and hepatic control region from the human apolipoprotein E (ApoE) gene, the human α-1- antitrypsin (hAAT) promoter, a chimeric human β-globin/IgG (HBB-IGG) intron, as well as a WPREmut6 region] and a bovine growth hormone (bGH) poly A sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats.
A recombinant, non-replicating adeno-associated viral vector serotype 6 (AAV6) encoding codon-optimised human alphagalactosidase A (GLA) under control of liver-specific regulatory elements [comprising enhancer and hepatic control region from the human apolipoprotein E (ApoE) gene, the human α-1- antitrypsin (hAAT) promoter, a chimeric human β-globin/IgG (HBB-IGG) intron, as well as a WPREmut6 region] and a bovine growth hormone (bGH) poly A sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats.
Структура
Иностранные названия
- Isaralgagenum civaparvovecum (латинское)
- Isaralgagene civaparvovec (английское)
- Isaralgagen civaparvovec (немецкое)
- Isaralgagène civaparvovec (французское)
- Isaralgagén civaparvovec (испанское)
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