Исувентатуг

Prop. INN (наименование, предложенное ВОЗ)

2986317-23-9

immunoglobulin G1-kappa, anti-[Homo sapiens MICA (MIC-A, MH1-like A) and Homo sapiens MICB (MIC-B, MH1-like B)], monoclonal antibody;
H-gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV3-11*01 (93.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS K2>del (450)) (122-450)], (224-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-137*01 (90.0%) -IGKJ4*01 (91.7%) S120>P (105')/Homo sapiens IGKV2-28*01 (86.0%) -IGKJ2*02 (90.9%) Q120>P (105'), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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