Изастобарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2769937-42-8

immunoglobulin G1-lambda, anti-[Homo sapiens C5AR1 (complement C5a receptor 1, C5R1, CD88)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-15*07 (92.9%) -(IGHD) -IGHJ3*01 (92.9%) M123>L (114), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v43 CH2 A1.3, E1.2, A1, G1v60 S115, S116 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>E (237), G1>A (239), A115>S (332), P116>S (333) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with lambda light chain Homo sapiens (1'-215') [V-LAMBDA (Homo sapiens IGLV1-44*04 (89.5%) -IGLJ2*01 (100%), CDR-IMGT [8.3.10] (26'-33'.51'-53'.90'-99')) (1'-109') -Homo sapiens IGLC2*01 (100%) (110'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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