Лафувитуг

Rec. INN (наименование, зарегистрированное ВОЗ)

2743342-91-6

immunoglobulin G1-kappa, anti-[HIV-1 (human immunodeficiency virus type 1) gp120 envelope glycoprotein, CD4-binding site)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV1-2*02 (62.7%) -(IGHD) -IGHJ3*01 (85.7%), CDR-IMGT [8.8.12] (26-33.51-58.101-112), FR3 insertion D84.1, F84.2, D85.2, T85.1 (77-80)) (1-123) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 (237-346), CH3 D12 (362), L14 (364) (347-451), CHS (452-453)) (124-453)], (226-206')-disulfide with kappa light chain Homo sapiens (1'-206') [V-KAPPA (Homo sapiens IGKV1-33*01 (72.8%) -IGKJ5*01 (41,6%) del (F118, G119,Q120) 92^93, E125>D (97), I126>L (98), CDR-IMGT [2.3.8] (27-28.46-48.85-92)) (1'-99') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (145), V101 (183) (100'-206')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHOK1SV, glycoform alfa

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