Ланеркитуг

Prop. INN (наименование, предложенное ВОЗ)

2839417-54-6

immunoglobulin G1-lambda2, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV3-23*01 (92.9%) -(IGHD) -IGHJ4*01 (93.3%)) [8.8.15] (26-33.51-58.97-111) (1-122) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-216')-disulfide with L-lambda2 light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV1-47*02 (89.9%) -IGLJ3*02 (100%), CDR-IMGT [9.3.11] (26'-34'.52'-54'.91'-101')) (1'-111') -Homo sapiens IGLC2*01 (100%) (112'-217')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from CHO-K1 cell line, lacking the glutamine synthetase (GS-KO) gene, and co-expressing the RMD enzyme (GDP-6-deoxy-d-lyxo-4-hexulose reductase), glycoform alfa

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