Ласрекибарт

Prop. INN (наименование, предложенное ВОЗ)

3021525-26-5

immunoglobulin G1-kappa, anti-[Homo sapiens IL5 (interleukin 5, IL-5)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-23*02 (88.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (215) (119-216), hinge 1-15 (217-231), CH2 M15.1>Y (253), S16>T (255), T18>E (257) (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-6*01 (84.0%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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