Лемзопарлимаб
LemzoparlimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2377483-71-9
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens CD47 (integrin associated protein, IAP, MER6, OA3)], monoclonal antibody;
gamma4 heavy chain (1-445) [VH (Homo sapiens IGHV3-15*07 (93.9%) -(IGHD) -IGHJ3*02 (100%)) CDR-IMGT [8.10.9] (26-33.51-60.99-107) (1-118) -Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-220')-disulfide with kappa light chain (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (89.1%) -IGKJ2*01 (90%) Q120>G (106)) CDR-IMGT [12.3.9] (27-38.56-58.95-103) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
gamma4 heavy chain (1-445) [VH (Homo sapiens IGHV3-15*07 (93.9%) -(IGHD) -IGHJ3*02 (100%)) CDR-IMGT [8.10.9] (26-33.51-60.99-107) (1-118) -Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-220')-disulfide with kappa light chain (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (89.1%) -IGKJ2*01 (90%) Q120>G (106)) CDR-IMGT [12.3.9] (27-38.56-58.95-103) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
Структура
Иностранные названия
- Lemzoparlimabum (латинское)
- Lemzoparlimab (английское)
- Lemzoparlimab (немецкое)
- Lemzoparlimab (французское)
- Lemzoparlimab (испанское)
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