Лесигерцепт

Prop. INN (наименование, предложенное ВОЗ)

2878448-12-3

human high affinity immunoglobulin epsilon receptor subunit alpha (Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha) extracellular domain fragment 26-205 (1-180 in the current sequence), fused to a Fc fragment of an hybrid human immunoglobulin D/G4 (181-425) [Homo sapiens IGHD*01 (hinge K¹⁹²>G, E¹⁹³>S (181-210)), Homo sapiens IGHG4*01 (CH2 E²¹¹>S, F²¹²>H, L²¹³>T, G²¹⁴>Q, G²¹⁵>P, P²¹⁶>L, S²¹⁷>G (209-217 matches IGHD*01) (211-318), CH3 (319-423), CHS (424-425))]; dimer (209-209')-disulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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