Липустобарт
LipustobartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2639481-06-2
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-447) [VH humanized (Homo sapiens IGHV1-46*01 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 L92 (309) (231-340), CH3 (341-445), CHS (446-447)) (121-447)], (134-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA Homo sapiens IGKV3D-11*01 (83.0%) -IGKJ4*01 (91.7%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
gamma4 heavy chain humanized (1-447) [VH humanized (Homo sapiens IGHV1-46*01 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 L92 (309) (231-340), CH3 (341-445), CHS (446-447)) (121-447)], (134-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA Homo sapiens IGKV3D-11*01 (83.0%) -IGKJ4*01 (91.7%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
Структура
Иностранные названия
- Lipustobartum (латинское)
- Lipustobart (английское)
- Lipustobart (немецкое)
- Lipustobart (французское)
- Lipustobart (испанское)
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