Ликсудебарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2749515-10-2

immunoglobulin G1-kappa, anti-[Homo sapiens CLDN1 (claudin-1) conformational epitope of the first extracellular loop (EL1)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-21*01 (94.9%) -(IGHD) -IGHJ1*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, CH2 IGHG1v39 CH2 F1.3, E1.2, S116 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>F (236) , L1.2>E (237), P116>S (333) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS K2>del (448)) (120-448)], (222-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-15*01 (84.2%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform al

C₆₄₄₂H₉₉₂₈N₁₇₂₆O₁₉₉₇S₄₄

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