Локиветмаб
LokivetmabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
1533403-95-0
Химическое название
immunoglobulin G2-kappa, anti-[Canis lupus familiaris IL31 (interleukin 31)], caninized monoclonal antibody;
gamma2 heavy chain (1-452) [caninized VH (Canis lupus familiaris IGHV-E2RCC8 (85.90%) -(IGHD)-IGHJ) [8.8.11] (1-118) -Canis lupus familiaris IGHG2*01 (CH1 (119-216), hinge (217-234), CH2 (235-344), CH3 (345-451), CHS (452)) (119-452)], (133-217')-disulfide with kappa light chain (1'-217') [caninized V-KAPPA (Canis lupus familiaris IGKV-F1PNY2 (56.00%) -IGKJ) [10.3.9] (1'-111') -Canis lupus familiaris IGKC*01 (112'-217')]; dimer (230-230'':233- 233'')-bisdisulfide
gamma2 heavy chain (1-452) [caninized VH (Canis lupus familiaris IGHV-E2RCC8 (85.90%) -(IGHD)-IGHJ) [8.8.11] (1-118) -Canis lupus familiaris IGHG2*01 (CH1 (119-216), hinge (217-234), CH2 (235-344), CH3 (345-451), CHS (452)) (119-452)], (133-217')-disulfide with kappa light chain (1'-217') [caninized V-KAPPA (Canis lupus familiaris IGKV-F1PNY2 (56.00%) -IGKJ) [10.3.9] (1'-111') -Canis lupus familiaris IGKC*01 (112'-217')]; dimer (230-230'':233- 233'')-bisdisulfide
Структура
Иностранные названия
- Lokivetmabum (латинское)
- Lokivetmab (английское)
- Lokivetmab (немецкое)
- Lokivetmab (французское)
- Lokivetmab (испанское)
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