Лорукафусп альфа

Rec. INN (наименование, зарегистрированное ВОЗ)

immunoglobulin G1-kappa, anti-(human ganglioside GD2) chimeric monoclonal antibody, fused with interleukin 2, glycoform alfa: gamma1 heavy chain [Mus musculus VH (Mus musculus IGHV1S135*01 (79.2%) -(IGHD)-IGHJ4*01 (92.9%)) [CDRKabatH1: GYNMN (31-35); CDRKabatH2: AIDPYYGGTSYNQKFKG (50-66); CDRKabatH3: GMEY (99-102)] (1-113) - Homo sapiens IGHG1*03 (CH1 (114-211), hinge (212-226), CH2 (227-336), CH3 (337-441), CHS (442-443))] (1- 443) fused with interleukin 2 (IL2, human) (444-576), (216-220')-disulfide with kappa light chain [V-KAPPA (Mus musculus IGKV1-110*01 (94.0%) -IGKJ5*01 (100.0%)) [CDRKabatL1: RSSQSLVHRNGNTYLH (24-39); CDRKabatL2: KVSNRFS (55-61); CDRKabatL3: SQSTHVPPLT (94-103)] (1'-113') - Homo sapiens IGKC*01 (114'-220')] (1'-220'), (222- 222'':225-225'')-bisdisulfide dimer, produced in mouse myeloma NS0 cells, glycoform alfa

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