Лумистобарт

Prop. INN (наименование, предложенное ВОЗ)

2851923-91-4

immunoglobulin G1-kappa, anti-[Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, protein tyrosine phosphatase non-receptor type substrate 1, PTPNS1, SIRP, SIRP alpha, CD172a)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV4-31*02 (93.9%) -(IGHD) -IGHJ4*01 (86.7%) L123>T (113), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v29 CH2 A84.4 (CH1 R120>K (215) (119-216), hinge 1-15 (217-231), CH2 N84.4>A (298) (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (91.1%) -IGKJ2*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159'), V101 (197') (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, non-glycosylated

Поделиться этой страницей