Лувагробарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2768355-18-4

immunoglobulin G1-kappa, anti-[Homo sapiens NGF (nerve growth factor, NGFB, nerve growth factor beta polypeptide)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV4-38-2*02 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.15] (26-33.51-57.96-110)) (1-121) -Homo sapiens IGHG1*01 (100%), G1m17,1, CH1 K120, CH3 D12, L14, G1v14 CH2 A1.3, A1.2 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>A (239) (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (86.3%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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